Current Research Posters at Conferences:
Articles in Journals:
1. B.A. Harley, M.H. Spilker, J.W. Wu, K.A. Asano, H.-P. Hsu, M. Spector, I.V. Yannas, ‘Optimal degradation rate for collagen chambers used for regeneration of peripheral nerves over long gaps,’ Cells Tissues Organs, 176(1-3):153-165, 2004.
2. F.J. O’Brien, B.A. Harley, I.V. Yannas, L.J. Gibson, ‘Influence of freezing-rate on pore structure in freeze-dried collagen-GAG scaffolds,’ Biomaterials, 25(6):1077-1086, 2004.
3. F.J. O’Brien, B.A. Harley, I.V. Yannas, L.J. Gibson, ‘The effect of pore size and structure on cell adhesion in collagen-GAG scaffolds,’ Biomaterials, 26(4):433-441, 2005.
4. B.A. Harley, A.Z Hastings, I.V. Yannas, A. Sannino, ‘Fabricating Tubular Scaffolds with a Radial Pore Size Gradient by a Spinning Technique,’ Biomaterials, 27(6):866-874, 2006.
5. E. Farrell, F.J. O’Brien, E. Byrne, P. Doyle, J. Fischer, I.V. Yannas, B.A. Harley, B. O’Connell, P.J. Prendergast, V.A. Campbell, ‘A collagen-glycosaminoglycan scaffold supports adult rat mesenchymal stem cell differentiation along the osteogenic and chrondrogenic routes,’ Tissue Engineering, 12(3):459-468, 2006.
6. B. Harley and I.V. Yannas, ‘Induced peripheral nerve regeneration using scaffolds,’ Minerva Biotecnologica, 18(2):97-120, 2006.
7. F.J. O’Brien, B.A. Harley, M.A. Waller, I.V. Yannas, L.J. Gibson, P.J. Prendergast, ‘The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering,’ Technol. Health Care, 15(1):3-17, 2007.
8. B.A. Harley, J.H. Leung, E. Silva, L.J. Gibson, ‘Mechanical characterization of collagen-glycosaminoglycan scaffolds,’ Acta Biomaterialia, 3(4):463-474, 2007.
9. B.A. Harley, T.M. Freyman, M.Q. Wong, L.J. Gibson, ‘A new technique for calculating individual dermal fibroblast contractile forces generated within collagen-GAG scaffolds,’ Biophys. J., 93(8):2911-2922, 2007.
10. Y. Le, B. Zhu, B. Harley, S.-Y. Park, J.P. Manis, H.R. Luo, A. Yoshimura, L. Hennighausen, L.E. Silberstein, ‘SOCS3 Protein Developmentally Regulates the Chemokine Receptor CXCR4-FAK Signaling Pathway during B Lymphopoiesis,’ Immunity, 27(5):811-823, 2007.
11. K.H. Kim, T. Ragan, K. Bahlmann, M.J.R. Previte, B.A. Harley, D.M. Wiktor-Brown, C.A. Hendricks, B.P. Engelward, M.S. Stitt, K.H. Almeida, P.T.C. So, ‘Three-dimensional tissue cytometer based on high-speed multiphoton microscopy,’ Cytometry A, 71(12):991-1002, 2007.
12. B.A. Harley, H.-D. Kim, M.H. Zaman, I.V. Yannas, D.A. Lauffenburger, L.J. Gibson, ‘Micro-architecture of three-dimensional scaffolds influences cell migration behavior via junction interactions,’ Biophys. J., 95(8):4013-24, 2008.
13. B.A.C. Harley and L.J. Gibson, ‘In vivo and in vitro applications of collagen-GAG scaffolds,’ Chemical Engineering Journal, 137:102-121, 2008.
14. A.K. Lynn, S.M. Best, R.E. Cameron, B.A. Harley, I.V. Yannas, L.J. Gibson, W. Bonfield, ‘Design of a Multiphase Osteochondral Scaffold I: Control of Chemical Composition,’ J. Biomed. Mater. Res. Part A, 92(3):1057-65, 2010.
15. B.A. Harley, A.K. Lynn, Z. Wissner-Gross, W. Bonfield, I.V. Yannas, L.J. Gibson, ‘Design of a Multiphase Osteochondral Scaffold II: Fabrication of a mineralized collagen-GAG scaffold,’ J. Biomed. Mater. Res. Part A, 92(3):1066-77, 2010.
16. B.A. Harley, A.K. Lynn, Z. Wissner-Gross, W. Bonfield, I.V. Yannas, L.J. Gibson, ‘Design of a Multiphase Osteochondral Scaffold III: Fabrication of Layered Scaffolds with Continuous Interfaces,’ J. Biomed. Mater. Res. Part A, 92(3):1078-93, 2010. Highlighted in:
17. I.V. Yannas, D.S. Tzeranis, B.A Harley, P.T.C. So, ‘Biologically active collagen-based scaffolds: Advances in processing and characterization,’ Philos Transact A Math Phys Eng Sci, 368(1917):2123-39, 2010.
18. A. Sannino, L. Silvestri, M. Madaghiele, B. Harley, I.V. Yannas, ‘Modeling the fabrication process of micropatterned macromolecular scaffolds for peripheral nerve regeneration,’ Journal of Applied Polymer Science, 116(4):1879-1888, 2010.
19. T. Martin‡, S.R. Caliari‡, P. Williford, B.A. Harley§, R.C. Bailey§, ‘The generation of biomolecular patterns in highly porous collagen-GAG scaffolds using direct photolithograph,’ Biomaterials, 32(16):3949-57, 2011.
‡ Co-first authors § Co-corresponding authors
20. S.R. Caliari, B.A.C. Harley, ‘The effect of anisotropic collagen-GAG scaffolds and growth factor supplementation on tendon cell recruitment, alignment, and metabolic activity,’ In Press, Biomaterials, 2011.
Chapters in Books:
1. B.A. Harley and I.V. Yannas, ‘Skin: Tissue Engineering for Regeneration,’ in J.G. Webster (ed.) The Encyclopedia of Medical Devices and Instrumentation, 2nd Edition, New York: Wiley, 2006.
2. B.A. Harley and I.V Yannas, ‘In Vivo Synthesis of Tissues and Organs,’ in R. Lanza, R. Langer, and J.P. Vacanti (eds.) Principles of Tissue Engineering, 3rd Edition, New York: Elsevier, 2007.
3. S.R. Caliari and B.A. Harley, ‘Collagen-GAG Materials,’ in P. Ducheyne (ed.) Comprehensive Biomaterials, Kidlington (UK): Elsevier, 2011.
Co-Authored Books:
1. L.J. Gibson, M.F. Ashby, B.A. Harley, ‘Cellular Materials in Nature and in Medicine,’ Cambridge University Press, 2010.
Co-Edited Books:
1. A. J. Wagoner Johnson and B.A.C. Harley (eds.), ‘Mechanobiology of Cell-Cell and Cell-Matrix Interactions,’ Springer, 2011.
Patents:
1. I.V. Yannas, L.J. Gibson, F.J. O’Brien, B.A. Harley, R.R. Brau, S. Samouhos, M. Spector, Gradient scaffolds and methods of producing the same, U.S. Patent Office Provisional Application 60/611,266, 2004.
2. A.K. Lynn, B.A. Harley, L.J. Gibson, I.V. Yannas, W. Bonfield, Biomaterial, U.K. Patent Application GB05/04673.5, March 7, 2005.
3. A. Sannino, B.A. Harley, A.Z Hasting, I.V. Yannas, A novel technique to fabricate cylindrical and tubular structures with a patterned porosity, International (PCT) Patent Application PCT/US2005/039024, October 27, 2005.
4. C.J. Zagorski, I.V Yannas, H.K. Reddy, B.A. Harley, Invaginated angiogenic scaffolds for regeneration of large organs, U.S. Patent Office Provisional Application 60/675,481, April 28, 2005.
5. B.A. Harley, C.J. Zagorski, H.K Reddy, I.V Yannas, Processing of angiogenic scaffolds for large organ replacement, U.S. Patent Office Provisional Application 60/730,880, October 28, 2005.
6. I.V Yannas, H.K. Reddy, C.J. Zagorski, B.A. Harley, Gradient template for angiogenesis during large organ regeneration, U.S. Patent Office Provisional Application 60/733,803, November 7, 2005.
7. Z. Wissner-Gross, B.A. Harley, A.K. Lynn, W. Bonfield, I.V. Yannas, L.J. Gibson, Layered, collagen-based scaffolds produced by solid-phase co-synthesis and solid-liquid co-synthesis, U.K. Patent Application GB06/16026.1, Aug. 11, 2006.